Meiosis

Meiosis
  • Similar in many ways to mitosis
  • Several differences
  • Involves 2 cell divisions
    • Results in 4 cells with 1/2 the normal genetic information.
  • Vocabulary:
  • Diploid (2N) - Normal amount of genetic material
  • Haploid (N) - 1/2 the genetic material.
  • Meiosis results in the formation of haploid cells.
  • In Humans, these are the Ova (egg) and sperm.
    • Ova are produced in the ovaries in females
      • Process is called oogenesis
    • Sperm are produced in the testes of males.
      • Process is called spermatogenesis
Spermatogenesis & Oogenesis
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  • Meiosis occurs in 2 phases; Meiosis I, & Meiosis II.
  • Meiosis I.
    • Prior to division, amount of DNA doubles
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    • During metaphase 1 homologous chromosomes line-up along the metaphase plate
    • Areas of homologous chromosomes connect at areas called chiasmata
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    • Crossing Over of genes occurs now.
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    • Segments of homologous chromosomes break and reform at similar locations.
    • Results in new genetic combinations of offspring.
      • This is the main advantage of sexual reproduction
 
    • During anaphase 1, each homologous chromosome is pulled to opposite sides of the cell. Unlike mitosis, THE CENTROMERES DO NOT BREAK.
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    • Nuclei may or may not reform following division.
    • Cytokenesis may or may not occur.
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  • Meiosis II.
    • DNA does not double
    • Chromosomes randomly line-up along metaphase plate like regular mitosis.
    • During anaphase 2, CENTROMERES BREAK and each chromosome is pulled to opposite sides of the cell.
    • Nuclei reform and cytokenesis usually occurs (although it is often unequal).
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