Meiosis
  - Similar in many ways to mitosis
 - Several differences
 - Involves 2 cell divisions
 - Results in 4 cells with 1/2 the normal genetic information.
 
- Vocabulary:
 
- Diploid (2N) - Normal amount of genetic material
 - Haploid (N) - 1/2 the genetic material.
 
- Meiosis results in the formation of haploid cells.
 - In Humans, these are the Ova (egg) and sperm.
 - Ova are produced in the ovaries in females
 - Process is called oogenesis
 - Sperm are produced in the testes of males.
 - Process is called spermatogenesis
 
Spermatogenesis & Oogenesis
  - Meiosis occurs in 2 phases; Meiosis I, & Meiosis II.
 
- Meiosis I.
 - Prior to division, amount of DNA doubles
 
- During metaphase 1 homologous chromosomes line-up along the metaphase plate
 - Areas of homologous chromosomes connect at areas called chiasmata
 
- Crossing Over of genes occurs now.
 
- Segments of homologous chromosomes break and reform at similar locations.
 - Results in new genetic combinations of offspring.
 - This is the main advantage of sexual reproduction
 
- During anaphase 1, each homologous chromosome is pulled to opposite sides of the cell. Unlike mitosis, THE CENTROMERES DO NOT BREAK.
 
- Nuclei may or may not reform following division.
 - Cytokenesis may or may not occur.
 
- Meiosis II.
 
- DNA does not double
 - Chromosomes randomly line-up along metaphase plate like regular mitosis.
 - During anaphase 2, CENTROMERES BREAK and each chromosome is pulled to opposite sides of the cell.
 
- Nuclei reform and cytokenesis usually occurs (although it is often unequal).
 
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